Publicações

Valorization of Hop (Humulus lupulus L.) Brewing Residue as a Natural Photoprotective Adjuvant

LIMA, A.G.U.B.; PINTO, C.A.S.O.; CÂNDIDO, T.M.; PESSOA, F.V.L.S.; VELASCO, M.V.R.; DEMARQUE, D.P.; BABY, A.R.

Photochem

DOI: 10.3390/photochem6010008

Plants Metabolites as In Vitro Inhibitors of SARS-CoV-2 Targets: A Systematic Review and Computational Analysis

GOMES, BRENDO ARAUJO; FERNANDES, DIÉGINA ARAÚJO; DA FONSECA, THAMIRYS SILVA; CAMPOS, MARIANA FREIRE; JURAL, PATRÍCIA ALVES; MARTINS, GABRIEL ROCHA; LEITÃO, GILDA GUIMARÃES; et al.

Drugs and Drug Candidates

Exploring the Epicarp Potential from Acrocomia aculeata Fruits: Chemical Analysis, Antioxidant and Antimicrobial Activities

SANTOS, FABIANE DA CONCEIÇÃO VIEIRA; MARTINS, GABRIEL ROCHA; LUIZ, SANDRA REGINA DA SILVA; OLIVEIRA, ISADORA DE ARAÚJO; SILVA, ANTONIO JORGE RIBEIRO DA; MORENO, DANIELA SALES ALVIANO; et al.

Antioxidants

Key Considerations for Sustainable Separations in Countercurrent Chromatography

MARTINS, GABRIEL ROCHA; DA CRUZ, ISABELLA LINA; FREIRE, ANDRÉ ATHAYDE DE FIGUEIREDO; FRANÇA, MARIANA MONTEIRO MATTOS; SILVA, AYLA SANT'ANA DA; HEWITSON, PETER; IGNATOVA, SVETLANA; COSTA, FERNANDA DAS NEVES

Journal of Separation Science

Development of a semi-preparative LC method for the purification of synthetic cannabinoids impregnated in herbal products for chemical characterization by NMR and HRMS

DE ARAÚJO, K.R.G.; DE PAULA MEIRELLES, G.; DEMARQUE, D.P.; DORR, F.; JÚNIOR, L.F.N.; et al.

Forensic Chemistry

DOI: 10.1016/j.forc.2025.100678

Effects of Long-Term Nutrient Addition on Leaf Metabolites, Herbivory, and Mycorrhizal Spores Associated With a Savannah Woody Species

MARTINS, A.; DEMARQUE, D.P.; DUSI, R.G.; SANTOS, C.A.C.; ESPINDOLA, L.S.; DA CUNHA BUSTAMANTE, M.M.

Austral Ecology

DOI: 10.1111/aec.70137

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of in Overweight Adults — A Double-Blind Trial

SANTAMARINA, A.B.; FILHO, V.N.; DE FREITAS, J.A.; HUFNAGEL, M.T.; DEMARQUE, D.P.; et al.

Molecular Nutrition & Food Research

DOI: 10.1002/mnfr.202400806

The extraction method determines the chemical profiles of leaves and stems of Melissa officinalis L.

FRAZÃO, V.P.; HUFNAGEL, M.T.; DÖRR, F.; PESSOA, A.F.M.; DEMARQUE, D.P.

Journal of Pharmacy & Pharmacognosy Research

DOI: 10.56499/jppres24.2245_13.5.1537

Antimicrobial and antibiofilm properties of procyanidins: potential for clinical and biotechnological applications

MATTOS, MARIANA M. G.; FILHO, SÉRGIO ANTUNES; MARTINS, GABRIEL R.; VENTURI, LARA SOUZA; CANETTI, VINÍCIUS BENJAMIM; FERREIRA, FABIENNE ANTUNES; FOGUEL, DEBORA; SILVA, AYLA SANT'ANA DA

Critical Reviews in Microbiology

New compounds from terrestrial plants: a perspective view

DEMARQUE, D.P.; et al.

Natural Product Reports

13aα-Densiindolizidine, A New Phenanthroindolizidine Alkaloid From Cryptocarya densiflora Blume (Lauraceae) and Molecular Docking Against SARS-CoV-2

OLIVEIRA, E.S.; KOHATSU, C.N.; HUFNAGEL, M.T.; GENNARO, V.F.; DEMARQUE, D.P.

Compounds

DOI: 10.3390/compounds4020025

Nutraceutical composition (yeast β-glucan, prebiotics, minerals, and silymarin) predicts improvement of sleep quality and metabolic parameters: A randomized pilot study

SANTAMARINA, A.B.; NEHMI FILHO, V.; DEMARQUE, D.P.; OLIVEIRA, E.S.; OTOCH, J.P.; PESSOA, A.F.M.; et al.

Clinical Nutrition ESPEN

DOI: 10.1016/j.clnesp.2024.06.033

New Compounds from Terrestrial Plants: A Perspective View

OLIVEIRA, E.S.; KOHATSU, C.N.; HUFNAGEL, M.T.; GENNARO, V.F.; DEMARQUE, D.P.

Compounds

DOI: 10.3390/compounds4020025

Edible Plant Extracts against Aedes aegypti and Validation of a Piper nigrum L. Ethanolic Extract as a Natural Insecticide

MORAIS, L.S.; SOUSA, J.P.B.; AGUIAR, C.M.; GOMES, C.M.; DEMARQUE, D.P.; ALBERNAZ, L.C.; ESPINDOLA, L.S.

Molecules

DOI: 10.3390/molecules28031264

Technological Aspects and Potential Cutaneous Application of Wine Industry By-Products

HÜBNER, A.A.; DE AGUIAR, M.M.G.B.; DEMARQUE, D.P.; ROSADO, C.; VELASCO, M.V.R.; KIKUCHI, I.S.; BABY, A.R.; PESSOA, F.V.L.S.

Applied Sciences

DOI: 10.3390/app13169068

Challenges, advances and opportunities in exploring natural products to control arboviral disease vectors

DEMARQUE, D.P.; et al.

Molecules

A synergistic Rh(I)/organoboron-catalysed site-selective carbohydrate functionalization that involves multiple stereocontrol

RAO, V.U.B.; WANG, C.; DEMARQUE, D.P.; GRASSIN, C.; OTTE, F.; MERTEN, C.; et al.

Nature Chemistry

DOI: 10.1038/s41557-022-01092-8

Phytocompounds Recovered from the Waste of Cabernet Sauvignon (Vitis vinifera L.) Vinification: Cytotoxicity and In Vitro Photoprotection Efficacy in a Sunscreen System

HÜBNER, A.A.; DEMARQUE, D.P.; LOURENÇO, F.R.; ROSADO, C.; BABY, A.R.; KIKUCHI, I.S.; BACCHI, E.M.

Cosmetics

DOI: 10.3390/cosmetics10010002

The acquisition of thin sections of açaí (Euterpe oleracea Mart.) seed with elevated potassium content for molecular mapping by mass spectrometry imaging

BRUM, FELIPE LOPES; MARTINS, GABRIEL R.; MOHANA-BORGES, RONALDO; SANT'ANA DA SILVA, AYLA

Rapid Communications in Mass Spectrometry

Preparation of Hard Palm Seeds for Matrix-Assisted Laser Desorption/Ionization-Imaging Mass Spectrometry Analysis

MARTINS, GABRIEL R.; BRUM, FELIPE L.; DA SILVA, DAVI MARCONI MIRANDA CARVALHO; BARBOSA, LIVIA C.; MOHANA-BORGES, RONALDO; DA SILVA, AYLA SANT'ANA

JoVE - Journal of Visualized Experiments

Combining chemometric and phytochemical tools to isolate and characterize activity of compounds against Aedes aegypti

MAGALHAES, N.M.G.; SOUSA, J.P.B.; DEMARQUE, D.P.; SALVADOR, C.E.M.; ALBERNAZ, L.C.; ACHEE, N.L.; GRIECO, J.P.; ESPINDOLA, L.S.

Natural Product Research

DOI: 10.1080/14786419.2021.1912747

Phenolic Profile and Antioxidant Properties in Extracts of Developing Açaí (Euterpe oleracea Mart.) Seeds

MARTINS, GABRIEL R.; MATTOS, MARIANA M. G.; NASCIMENTO, FABIANE MARQUES; BRUM, FELIPE L.; MOHANA-BORGES, RONALDO; FIGUEIREDO, NATÁLIA GUIMARÃES; SANT'ANA DA SILVA, AYLA; et al.

Journal of Agricultural and Food Chemistry

Proteomic changes associated with the development of açaí (Euterpe oleracea Mart.) seeds

NETO, DOMINGOS F. M.; NASCIMENTO, JOSÉ R. S.; MARTINS, GABRIEL R.; SILVA, AYLA S.; DOMONT, GILBERTO B.; CAMPOS, FRANCISCO A. P.; NOGUEIRA, FÁBIO C. S.

Proteomics

Challenges, Advances and Opportunities in Exploring Natural Products to Control Arboviral Disease Vectors

DEMARQUE, D.P.; ESPINDOLA, L.S.

Frontiers in Chemistry

DOI: 10.3389/fchem.2021.779049

Cucurbitane Triterpene Glycosides from the Roots of Wilbrandia hibiscoides

FIORI, G.M.L.; DEMARQUE, D.P.; PEREIRA, A.M.S.; KLEIN, V.L.G.; LOPES, N.P.

Brazilian Journal of Pharmacognosy

DOI: 10.1007/s43450-021-00172-3

The Potential of Biologically Active Brazilian Plant Species as a Strategy to Search for Molecular Models for Mosquito Control

VALLI, M.; ATANÁZIO, L.C.V.; MONTEIRO, G.C.; COELHO, R.R.; DEMARQUE, D.P.; ANDRICOPULO, A.D.; ESPINDOLA, L.S.; BOLZANI, V.S.

Planta Medica

DOI: 10.1055/a-1320-4610

Rapid Microwave-Assisted Phloroglucinolysis in the Determination of Oligomeric Procyanidin Average Size in Fiber Extracts of Two Cocos nucifera L. Varieties

MARTINS, G. R.; BORGES, R.M.; ALVIANO, C. S.; ALVIANO, D. S.; da SILVA, A. J. R.

Revista Virtual de Química

Açaí (Euterpe oleracea Mart.) Seed Extracts from Different Varieties: A Source of Proanthocyanidins and Eco-Friendly Corrosion Inhibition Activity

MARTINS, GABRIEL ROCHA; GUEDES, DOUGLAS; MARQUES DE PAULA, URBANO LUIZ; DE OLIVEIRA, MARIA DO SOCORRO PADILHA; ALVIANO, CELUTA SALES; RIBEIRO DA SILVA, ANTONIO JORGE; ALVIANO, DANIELA SALES; et al.

Molecules

Proanthocyanidins with Corrosion Inhibition Activity for AISI 1020 Carbon Steel under Neutral pH Conditions of Coconut (L.) Husk Fibers

GUEDES, DOUGLAS; MARTINS, GABRIEL R.; JARAMILLO, LIZETH Y. A.; SIMAS BERNARDES DIAS, DIOGO; DA SILVA, ANTONIO JORGE R.; ALVIANO, CELUTA S.; ALVIANO, DANIELA S.; et al.

ACS Omega

A validated Folin-Ciocalteu method for total phenolics quantification of condensed tannin-rich açaí (Euterpe oleracea Mart.) seeds extract

MARTINS, GABRIEL ROCHA; MONTEIRO, ALVARO FERREIRA; DO AMARAL, FELIPE RAFAEL LOPES; DA SILVA, AYLA SANT'ANA

Journal of Food Science and Technology

A molecular networking strategy: high-throughput screening and chemical analysis of Brazilian cerrado plant extracts against cancer cells

CORTELO, P.C.; DEMARQUE, D.P.; DUSI, R.G.; ALBERNAZ, L.C.; BRAZ-FILHO, R.; GONCHAROVA, E.I.; ESPINDOLA, L.S.; et al.

Cells

DOI: 10.3390/cells10030691

VCD spectroscopy reveals that a water molecule determines the conformation of azithromycin in solution

DEMARQUE, D.P.; KEMPER, M.; MERTEN, C.

Chemical Communications

DOI: 10.1039/D1CC00932J

Antileishmanial compounds from Connarus suberosus: Metabolomics, isolation and mechanism of action

MORAIS, L.S.; DUSI, R.G.; DEMARQUE, D.P.; SILVA, R.L.; ALBERNAZ, L.C.; BÁO, S.N.; MERTEN, C.; ESPINDOLA, L.S.; et al.

PLoS One

DOI: 10.1371/journal.pone.0241855

Chemical characterization, antioxidant and antimicrobial activities of açaí seed (Euterpe oleracea Mart.) extracts containing A- and B-type procyanidins

MARTINS, GABRIEL R.; DO AMARAL, FELIPE RAFAEL L.; BRUM, FELIPE L.; MOHANA-BORGES, RONALDO; FERREIRA, FABIENNE A.; SANGENITO, LEANDRO S.; SANTOS, ANDRÉ L.S.; FIGUEIREDO, NATÁLIA G.; SANT'ANA DA SILVA, AYLA; et al.

LWT - Food Science and Technology

Residual Larvicidal Activity of Quinones against Aedes aegypti

SILVA, R.L.; DEMARQUE, D.P.; DUSI, R.G.; SOUSA, J.P.B.; ALBERNAZ, L.C.; ESPINDOLA, L.S.

Molecules

DOI: 10.3390/molecules25173978

Absolute Stereochemistry of Antifungal Limonene-1,2-diols from Lippia rubella

LEITÃO, SUZANA GUIMARÃES; MARTINS, GABRIEL R.; MARTÍNEZ-FRUCTUOSO, LUCERO; DE SOUSA SILVA, DANILA; DA FONSECA, THAMIRYS SILVA; ALVIANO, DANIELA S.; ALVIANO, CELUTA SALES; LEITÃO, GILDA GUIMARÃES; PEREDA-MIRANDA, ROGELIO

Brazilian Journal of Pharmacognosy

Dereplication and Isolation of Larvicidal Compounds From Annonaceae Species Against Aedes aegypti

DE SOUSA, F.D.M.; GROSSI, S.M.; MONTEIRO, G.C.; DEMARQUE, D.P.; ESPINDOLA, L.S.

Brazilian Journal of Pharmacognosy

DOI: 10.1007/s43450-020-00018-4

Involvement of Isoorientin in the Antidepressant Bioactivity of a Flavonoid-Rich Extract from Passiflora edulis f. flavicarpa Leaves

ALVES, J.S.F.; MARQUES, J.I.; DEMARQUE, D.P.; COSTA, L.R.F.; AMARAL, J.G.; LOPES, N.P.; ZUCOLOTTO, S.M.; et al.

Brazilian Journal of Pharmacognosy

DOI: 10.1007/s43450-020-00003-x

Mass spectrometry-based metabolomics approach in the isolation of bioactive natural products

DEMARQUE, D.P.; DUSI, R.G.; DE SOUSA, F.D.M.; GROSSI, S.M.; SILVÉRIO, M.R.S.; LOPES, N.P.; ESPINDOLA, L.S.

Scientific Reports

DOI: 10.1038/s41598-020-58046-y

Sensitivity of VCD spectroscopy for small structural and stereochemical changes of macrolide antibiotics

DEMARQUE, D.P.; HEINRICH, S.; SCHULZ, F.; MERTEN, C.

Chemical Communications

DOI: 10.1039/D0CC03838E

Synthesis, phytotoxic evaluation and in silico studies for the development of novel natural products-inspired herbicides

RODRIGUES, R.P.; BARONI, A.C.M.; CAROLLO, C.A.; DEMARQUE, D.P.; DE SIQUEIRA, J.M.; et al.

Biocatalysis and Agricultural Biotechnology

DOI: 10.1016/j.bcab.2020.101559

Pharmacokinetic disposition of erythraline in rats after intravenous administration

DEMARQUE, D.P.; CALLEJON, D.R.; PINTO, L.G.; GOUVEA, D.R.; DE MORAES, N.V.; LOPES, J.L.C.; LOPES, J.N.C.; LOPES, N.P.; GUARATINI, T.

Revista Brasileira de Farmacognosia

DOI: 10.1016/j.bjp.2019.07.002

Antifungal Phenylpropanoid Glycosides from Lippia rubella

MARTINS, GABRIEL R.; DA FONSECA, THAMIRYS SILVA; MARTÍNEZ-FRUCTUOSO, LUCERO; SIMAS, ROSINEIDE COSTA; SILVA, FABIO T.; SALIMENA, FATIMA REGINA G.; ALVIANO, DANIELA S.; ALVIANO, CELUTA SALES; LEITÃO, GILDA GUIMARÃES; PEREDA-MIRANDA, ROGELIO; LEITÃO, SUZANA G.

Journal of Natural Products

Isolation and Identification of the Five Novel Flavonoids from Genipa americana Leaves

SILVA, L.M.P.; ALVES, J.S.F.; DA SILVA SIQUEIRA, E.M.; DE SOUZA NETO, M.A.; ABREU, L.S.; DEMARQUE, D.P.; et al.

Molecules

DOI: 10.3390/molecules23102521

Coconut Husk Fiber Proanthocyanidins: Ecofriendly Corrosion Inhibitor, Ecotoxicity and Biocide Activity

GUEDES, D.; MARTINS, G. R.; ALVIANO, D. S.; LUTTERBACH, M. T. S.; REZNIK, L. Y.; SERVULO, E. F. C.

International Journal of Engineering and Technical Research

Revisiting empirical rules for the determination of the absolute configuration of cascarosides and other (ox-)anthrones

DEMARQUE, D.P.; PINHO, D.R.; LOPES, N.P.; MERTEN, C.

Chirality

DOI: 10.1002/chir.22803

Cytotoxicity of Structurally Diverse Anthranoids and Correlation with Mechanism of Action and Side Effects

DEMARQUE, D.P.; SILVA, R.M.P.; SANTOS, L.F.; LEOPOLDINO, A.M.; ESPREAFICO, E.M.; LOPES, N.P.

Journal of Pharmacy and Pharmaceutical Sciences

DOI: 10.18433/jpps30077

The role of tannins as antiulcer agents: a fluorescence-imaging based study

DEMARQUE, D.P.; CALLEJON, D.R.; DE OLIVEIRA, G.G.; SILVA, D.B.; CAROLLO, C.A.; et al.

Revista Brasileira de Farmacognosia

DOI: 10.1016/j.bjp.2018.03.011

Cytotoxic Triterpenes from Salacia crassifolia and Metabolite Profiling of Celastraceae Species

ESPINDOLA, L.S.; DUSI, R.G.; DEMARQUE, D.P.; BRAZ-FILHO, R.; YAN, P.; BOKESCH, H.R.; et al.

Molecules

DOI: 10.3390/molecules23061494

Achyrocline alata potentiates repair of skin full thickness excision in mice

PEREIRA, L.X.; SILVA, H.K.C.; LONGATTI, T.R.; CAROLLO, C.A.; DEMARQUE, D.P.; DE SIQUEIRA, J.M.; et al.

Journal of Tissue Viability

DOI: 10.1016/j.jtv.2017.09.005

New cascarosides from Rhamnus purshiana and fragmentation studies of the class by IT-MS

DEMARQUE, D.P.; PINHO, D.R.; CALLEJON, D.R.; DE OLIVEIRA, G.G.; SILVA, D.B.; CAROLLO, C.A.; LOPES, N.P.

Rapid Communications in Mass Spectrometry

DOI: 10.1002/rcm.7883

Intra- versus Intermolecular Hydrogen Bonding: Solvent-Dependent Conformational Preferences of a Common Supramolecular Binding Motif from 1H NMR and VCD Spectroscopy

DEMARQUE, D.P.; MERTEN, C.

Chemistry - A European Journal

DOI: 10.1002/chem.201703643

Dereplication of flavonoid glycoconjugates from Adenocalymma imperatoris-maximilianii by untargeted tandem mass spectrometry-based molecular networking

DE OLIVEIRA, G.G.; NETO, F.C.; DEMARQUE, D.P.; DE SOUSA PEREIRA-JUNIOR, J.A.; et al.

Planta Medica

DOI: 10.1055/s-0042-118712

Characterization of anti-inflammatory effect and possible mechanism of action of Tibouchina granulosa

SOBRINHO, ANDREA P.; MINHO, ALAN S.; FERREIRA, LEIDE L.C.; MARTINS, GABRIEL R.; BOYLAN, FABIO; FERNANDES, PATRICIA D.

Journal of Pharmacy and Pharmacology

Fragmentation reactions using electrospray ionization mass spectrometry: an important tool for the structural elucidation and characterization of synthetic and natural products

DEMARQUE, D.P.; CROTTI, A.E.M.; VESSECCHI, R.; LOPES, J.L.C.; LOPES, N.P.

Natural Product Reports

DOI: 10.1039/c5np00073d

Diterpenes and a new benzaldehyde from the mangrove plant Rhizophora mangle

MARTINS, JHESSICA N.; FIGUEIREDO, FABIANA S.; MARTINS, GABRIEL R.; LEITÃO, GILDA G.; COSTA, FERNANDA N.

Revista Brasileira de Farmacognosia

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

WANG, M.; CARVER, J.J.; PHELAN, V.V.; SANCHEZ, L.M.; GARG, N.; DEMARQUE, D.P.; LOPES, N.P.; DORRESTEIN, P.C.; et al.

Nature Biotechnology

DOI: 10.1038/nbt.3597

In vitro anti-Leishmania infantum activity of essential oil from Piper angustifolium

BOSQUIROLI, L.S.S.; DEMARQUE, D.P.; RIZK, Y.S.; CUNHA, M.C.; MARQUES, M.C.S.; et al.

Revista Brasileira de Farmacognosia

DOI: 10.1016/j.bjp.2015.03.008

Euterpe oleracea Mart.-Derived Polyphenols Protect Mice from Diet-Induced Obesity and Fatty Liver by Regulating Hepatic Lipogenesis and Cholesterol Excretion

DE OLIVEIRA, PAOLA RAQUEL B.; DA COSTA, CRISTIANE A.; MARTINS, GABRIEL R.; DA SILVA, ANTÔNIO JORGE R.; DE MOURA, ROBERTO S.; RESENDE, ANGELA C.; et al.

Plos One

Optimization and Technological Development Strategies of an Antimicrobial Extract from Achyrocline alata Assisted by Statistical Design

DEMARQUE, D.P.; FITTS, S.M.F.; BOARETTO, A.G.; DA SILVA, J.C.L.; VIEIRA, M.C.; CAROLLO, C.A.; et al.

PLoS One

DOI: 10.1371/journal.pone.0118574

Low expression of CD39 on regulatory T cells as a biomarker for resistance to methotrexate therapy in rheumatoid arthritis

PERES, R.S.; LIEW, F.Y.; TALBOT, J.; DEMARQUE, D.P.; GOUVEA, D.R.; LOPES, N.P.; CUNHA, F.Q.; et al.

Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.1424792112

Physicochemical, microbiological and sensory evaluation of a bioactive food blend

FERREIRA, R.S.; HIANE, P.A.; GUIMARÃES, R.C.A.; RAMOS, M.I.L.; DEMARQUE, D.P.; MEIRA, J.E.C.

Ciência e Tecnologia de Alimentos

DOI: 10.1590/1678-457x.6406

Chemical and antimicrobial analysis of husk fiber aqueous extract from Cocos nucifera L.

SILVA, D. O.; MARTINS, G. R.; da SILVA, A. J. R.; ALVIANO, D. S.; NASCIMENTO, R. P.; KAPLAN, M.A.C.; ALVIANO, C. S.

African Journal of Biotechnology

Polyphenolics from two Brazilian species of the arecaceae family

MARTINS, GR; SILVA, DO; ALVIANO, DS; KAPLAN, MAC; ALVIANO, CS; DA SILVA, AJR

Planta Medica

Allelopathic activity of Matricaria chamomilla essential oil by the bioautography test

DEMARQUE, D.P.; SABOIA, J.F.; FABRI, J.R.; CAROLLO, C.A.

Allelopathy Journal

In vitro inhibitory effect of Urera baccifera (L.) Gaudich. extracts against herpes simplex

Fernanda Otaviano Martins; Michelle Mendes da Rocha Gomes; NOGUEIRA, Fábio Luis Pereira; MARTINS, G. R.; ROMANOS, M. T. V.; KAPLAN, Maria Auxiliadora Coelho; MENEZES, Fábio de Sousa

African Journal of Pharmacy and Pharmacology